Preheat the oven to 325 degrees F. Line a 9x5 inch loaf pan with parchment paper and grease with cooking spray.
In a medium mixing bowl, combine the flour, baking soda, baking powder, and salt with a whisk. Set aside.
In a large mixing bowl with a hand mixer, beat the butter and sugar until light and fluffy.
Add the eggs, lemon zest, lemon juice, and vanilla. Mix until combined.
Mix on low speed while gradually adding the flour mixture until completely combined. Add the greek yogurt and mix until combined. If desired, you can add a couple drops of yellow food coloring at a time until the desired color is reached.
Spoon the batter into the prepared loaf pan, and bake for 50-55 minutes or until a toothpick can be inserted and come out clean.
Allow the loaf to cool in the pan for 15 minutes, before removing and allowing to finish cooling on a wire rack.